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KMID : 1134820210500020128
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Journal of the Korean Society of Food Science and Nutrition
2021 Volume.50 No. 2 p.128 ~ p.135
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Inhibitory Effects of Zingiber officinale Roscoe Roots, Stems, and Leaves on Oxidative Stress through Free Radical Scavenging Activity
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Im Pu-Reum
Hwang Hye-Jeong
Im Jeong-Yeon
Hwang Yu-Jin
Nam Dong-Geon
Choe Jeong-Sook
Hwang Kyung-A
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Abstract
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In this study, the antioxidant effects of Zingiber officinale Roscoe leaves and stems which have been registered as new food ingredients were comparatively analyzed with Z. officinale Rosc. roots. The increase in antioxidant activity was concentration-dependent in all extracts, and excellent antioxidant activity was confirmed in the roots (58%) and leaves (35%) at 100 μg/mL. The inhibitory effect of nitric oxide production was found in all samples. In particular, the leaves showed an inhibitory rate of 25∼31%, an effect similar to that of the roots (22∼37%), confirming their excellent efficacy. The stems showed a 24∼26% inhibition rate, but the inhibition was not concentration-dependent. The inhibitory effect of the roots, stems and leaves of Z. officinale Rosc. on the reactive oxygen species production was highest in the roots (21∼46%), followed by leaves (15∼30%) and stems (2∼11%). Cu/Zn-superoxide dismutase (SOD) and Mn-SOD mRNA expressions were increased to high levels by the leaves. Glutathione peroxidase and catalase levels were in the increased in the roots, leaves, and stems, in that order. Through the results of this study, the antioxidant effects of Z. officinale Rosc. leaves and stems were confirmed, and excellent antioxidant activity was confirmed in the leaves. Z. officinale Rosc. leaves can therefore be considered for use as an antioxidant functional health food material in the future. However, since studies on the leaves are insufficient, additional studies in animals are needed to investigate the mechanism of the physiological activity of Z. officinale Rosc. leaves in the body.
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KEYWORD
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Zingiber officinale Roscoe, root, leaf, stem, reactive oxidative stress
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